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Nadja Paeslack Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Germany

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Christoph Reinhardt Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Germany
German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany

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extrinsic nutritional factor that was demonstrated to increase mucosal thickness and villus length in the small intestine ( Todorov et al. 2020 ). In contrast, epithelial-to-mesenchymal signaling by endogenous intrinsically synthetized morphogens, such as

Article Type:
Review Article
DOI:
https://doi.org/10.1530/MAH-23-0021
Volume/Issue:
Volume 2: Issue 1
Open access
Victoria Poplaski Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA

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Faith Sawyer Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA

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Sarah E Blutt Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA

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composition in the small intestine ( Human Microbiome Project 2012 ), and a recent focus on the functionality of these organisms has resulted in the discovery that the microbiome and ISCs have an intimate relationship ( Peck et al. 2017 ). This review will

Article Type:
Review Article
DOI:
https://doi.org/10.1530/MAH-23-0012
Volume/Issue:
Volume 1: Issue 1
Open access
Sweta Ghosh Department of Microbiology and Immunology, Brown Cancer Center, Center for Microbiomics, Inflammation and Pathogenicity, University of Louisville, Louisville, Kentucky, United States of America

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Syam P Nukavarapu Department of Biomedical Engineering and Department of Materials Science & Engineering, University of Connecticut, Storrs, Connecticut, United States of America

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Venkatakrishna Rao Jala Department of Microbiology and Immunology, Brown Cancer Center, Center for Microbiomics, Inflammation and Pathogenicity, University of Louisville, Louisville, Kentucky, United States of America

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risk of diseases such as Crohn's disease in humans ( Cray et al. 2021 ). M cells are specialized epithelial cells found in the gut-associated lymphoid tissue (GALT) of Peyer’s patches of the small intestine, isolated lymphoid follicles, colonic

Article Type:
Review Article
DOI:
https://doi.org/10.1530/MAH-23-0015
Volume/Issue:
Volume 2: Issue 1
Open access
John Henry Dasinger Department of Physiology, Medical College of Georgia, Augusta University, Augusta, Georgia, USA

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Bina Joe Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA

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Justine M Abais-Battad Department of Physiology, Medical College of Georgia, Augusta University, Augusta, Georgia, USA

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fatty acids directly impact central nervous system autoimmunity via the small intestine . Immunity 43 817 – 829 . ( https://doi.org/10.1016/j.immuni.2015.09.007 ) Haro C Rangel-Zuniga OA Alcala-Diaz JF , 2016 Intestinal microbiota is influenced

Article Type:
Review Article
DOI:
https://doi.org/10.1530/MAH-23-0016
Volume/Issue:
Volume 1: Issue 1
Open access