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Elizabeth A Coler Department of Chemistry, University of Connecticut, Storrs, Connecticut, USA

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Wanxuan Chen Department of Chemistry, University of Connecticut, Storrs, Connecticut, USA

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Alexey V Melnik Department of Chemistry, University of Connecticut, Storrs, Connecticut, USA
Arome Science Inc., Farmington, Connecticut, USA

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James T Morton Gutz Analytics LLC, Boulder, Colorado, USA

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Alexander A Aksenov Department of Chemistry, University of Connecticut, Storrs, Connecticut, USA
Arome Science Inc., Farmington, Connecticut, USA

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Introduction Metabolomics is a relatively new discipline within the field of science, emerging as a crucial component in the study of biological systems. Over the past few decades, particularly since the late 20th century and into the early 21

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John Henry Dasinger Department of Physiology, Medical College of Georgia, Augusta University, Augusta, Georgia, USA

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Bina Joe Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA

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Justine M Abais-Battad Department of Physiology, Medical College of Georgia, Augusta University, Augusta, Georgia, USA

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, metabolite diversity may even surpass microbial diversity ( Dorrestein et al. 2014 ). Further emphasizing the potential importance of these systemic factors, sex is a critical determinant of the overall metabolomic profile, with >50% of all metabolites

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Andrija Karačić Department of General Surgery, University Hospital Sveti Duh, Zagreb, Croatia
The Gut Microbiome Center (CCM), Zagreb, Croatia

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Jasna Novak Department of Biochemical Engineering, University of Zagreb Faculty of Food Technology and Biotechnology Faculty, Zagreb, Croatia

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Alan Ivković Department of Orthopaedics and Traumatology, University Hospital Sveti Duh, Zagreb, Croatia
School of Medicine, University of Zagreb, Zagreb, Croatia
Department of Clinical Medicine, University of Applied Health Sciences, Zagreb, Croatia

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various probiotic strains such as A.muciniphila, B.adolescentis , and Lactobacillus gasseri . In the context of probiotic administration in fracture treatment, the metabolomic aspect of the gut microbiome and probiotics is crucial. SCFAs, the main

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John C Alverdy University of Chicago Division of the Biological Sciences, Chicago, Illinois, USA

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palatable oral solution available to drink two to three times a day that could maintain the resilience and metabolomics output of the gut microbiome, it would be highly desirable. In addition, if such a solution were verified to reduce complex complications

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Muhammad Hassan Saeed Intestinal Microbiome, School of Life Sciences, ZIEL – Institute for Food & Health, Technical University of Munich, Freising, Germany

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Lindsay J Hall Intestinal Microbiome, School of Life Sciences, ZIEL – Institute for Food & Health, Technical University of Munich, Freising, Germany
Gut Microbes & Health, Quadram Institute Bioscience, Norwich Research Park, Norwich, UK
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK

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Unraveling the microbiome of necrotizing enterocolitis: insights in novel microbial and metabolomic biomarkers . Microbiology Spectrum 9 e0117621 . ( https://doi.org/10.1128/Spectrum.01176-21 ) Tfifha M Ferjani A Mallouli M , 2018 Carriage of multidrug

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Sweta Ghosh Department of Microbiology and Immunology, Brown Cancer Center, Center for Microbiomics, Inflammation and Pathogenicity, University of Louisville, Louisville, Kentucky, United States of America

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Syam P Nukavarapu Department of Biomedical Engineering and Department of Materials Science & Engineering, University of Connecticut, Storrs, Connecticut, United States of America

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Venkatakrishna Rao Jala Department of Microbiology and Immunology, Brown Cancer Center, Center for Microbiomics, Inflammation and Pathogenicity, University of Louisville, Louisville, Kentucky, United States of America

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J Chen W Sun Y , et al. 2021a Effects of cadmium on organ function, gut microbiota and its metabolomics profile in adolescent rats . Ecotoxicology and Environmental Safety 222 112501 . ( https://doi.org/10.1016/j.ecoenv.2021.112501 ) Yang

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